A fine example of a mid-sixteenth century Mesue's works, in two translations, one ‘antique,’ the other by Jacobus Sylvius (Jacques Dubois, 1478-1555), the celebrated Parisian teacher of anatomy. The Medieval Latin translation of the treatise on simple drugs had been traditionally attributed to a Pseudo-Mesue (also called Johannes Mesue the Younger). The anonymous translation was made between 1260 and 1290. Born in 777/161 into a family of physicians from Gondishapur, in western Iran, Yūḥannā ibn Masawayh (known to Europeans as Mesuë or filius Mesuë) became court physician to the caliph in Baghdad and director of a hospital there. His pupil was Ḥunayn ibn Isḥāq, and he himself composed medical treatises on a number of topics, including ophthalmology, fevers, headache, melancholia, dietetics, the testing of physicians, and medical aphorisms. Included in this edition are the commentaries of Giovanni Manardi on Mesue’s "De simplicibus medicamentis purgantibus" and "Grabadin," (Antidotarium) and a glossary to the latter by Sylvius. Mesue’s text and the commentaries thereon are here accompanied as usual by various other texts, including Albucasis’ "Liber servitoris" and Al-Kindi’s "De medicinarum compositarum gradibus investigandis."